\n\nMethods: Neurocognitive functioning and psychopathology were assessed in (i) 76 patients with bipolar disorder, (ii) 39 of their healthy first-degree relatives, and (iii) 61 healthy controls. Cognitive performance of bipolar patients and their. rst-degree relatives was investigated, taking into account the possible moderating effect of the level of expression of psychosis in patients and relatives.\n\nResults: Bipolar patients showed impaired cognitive performance
on multiple cognitive domains, whereas performance of their relatives was comparable to that of controls. A history of psychotic symptoms in patients was suggestive of less likelihood of cognitive alterations in relatives, and the presence of subclinical Cl-amidine order psychotic symptoms within the group of relatives predicted better cognitive performance.\n\nConclusions: The finding of similar psychosis-cognition associations in bipolar disorder as implied by the two pathways leading to nonaffective psychotic disorders suggests that this model might be extended to the continuum spanning affective and nonaffective psychosis. This is in line with the idea of a partially overlapping vulnerability to bipolar disorder and schizophrenia and provides an explanation for the apparent differences in cognitive alterations
in those at risk for the two disorders.”
“We investigated the effects of honey and its methanol and ethyl acetate extracts on inflammation in animal models. Rats’ paws were induced this website with carrageenan in the non-immune inflammatory and nociceptive model, and lipopolysaccharide (LPS) in the immune inflammatory model. Honey and its extracts were able to inhibit edema and pain in inflammatory tissues as well as showing potent inhibitory activities against NO and PGE(2) in both models. The decrease in edema and pain correlates
with the inhibition of NO and PGE(2). Phenolic Cytoskeletal Signaling inhibitor compounds have been implicated in the inhibitory activities. Honey is potentially useful in the treatment of inflammatory conditions. (C) 2010 Elsevier B.V. All rights reserved.”
“The objective was to identify legume shrub species for development of agroforestry technologies based on seed and forage (leaves and twigs < 10 mm diameter)yield, and determinants of forage quality. Ten individual plants of Bituminaria bituminosa ‘Ecotypes 1′, B. bituminosa ‘Ecotypes 2′, Medicago citrina, and M. arborea from Spain; Colutea istria and Onobrychis aurantiaca from Syria; C. istria from Jordan; Chamaecytisus moths from Morocco; and Coronilla glauca from France were randomly selected from plots established in a nontropical dryland environment in northwest Syria in 2000. Five individual plants of each species were cut back to 0.5 m above ground in March 2004.