J Exp Med 1997, 185:1759–1768.PubMed 107. Hasko G, Kuhel DG, Marton A, Nemeth ZH, Deitch EA, Szabo C: Spermine differentially regulates the production of interleukin-12 p40 and interleukin-10 and suppresses the release of the T helper 1 cytokine interferon-gamma. Shock 2000, 14:144–149.PubMed 108. Bowlin TL, McKown BJ, Sunkara PS: The effect of alpha-difluoromethylornithine, an inhibitor of polyamine biosynthesis, on mitogen-induced interleukin 2 production. Immunopharmacology CH5424802 1987, 13:143–147.PubMed 109. Chamaillard L, Quemener V, Havouis R, Moulinoux JP: Polyamine deprivation

stimulates natural killer cell activity in cancerous mice. Anticancer Res 1993, 13:1027–1033.PubMed 110. Carswell EA, Old LJ, Kassel RL, Green S, Fiore N, Williamson B: An endotoxin-induced serum factor that causes necrosis of tumors.

Proc Natl Acad Sci USA 1975, 72:3666–3670.PubMed 111. Wacholtz MC, Patel SS, Lipsky PE: Leukocyte function-associated antigen 1 is an activation molecule for human T cells. J Exp Med 1989, 170:431–448.PubMed 112. Ferrini S, Sforzini S, Cambiaggi A, Poggi A, Meazza R, Canevari S, Colnaghi MI, Moretta L: The click here LFA-1/ICAM cell adhesion pathway is involved in tumor-cell lysis mediated by bispecific monoclonal-antibody-targeted T lymphocytes. Int J Cancer 1994, 56:846–852.PubMed 113. Sarhan S, Weibel M, Seiler N: Effect of polyamine deprivation on the survival of intracranial glioblastoma bearing rats. Anticancer Res

1991, 11:987–992.PubMed 114. Seiler N, Sarhan S, Grauffel C, Jones R, Knodgen B, Moulinoux JP: Endogenous and exogenous polyamines in support of tumor growth. Cancer Res 1990, 50:5077–5083.PubMed 115. Cipolla BG, Havouis R, Moulinoux JP: Polyamine reduced diet (PRD) nutrition therapy in hormone refractory prostate cancer patients. Biomed Pharmacother 2010, 64:363–368.PubMed 116. Page GG, Ben-Eliyahu S, Liebeskind JC: The role of LGL/NK cells in surgery-induced promotion of metastasis and its attenuation by morphine. Brain Behav Immun 1994, 8:241–250.PubMed 117. Pollock RE, Babcock 5 FU GF, Romsdahl MM, Nishioka K: Surgical stress-mediated suppression of murine natural killer cell cytotoxicity. Cancer Res 1984, 44:3888–3891.PubMed 118. Hattori T, Hamai Y, Harada T, Ikeda H, Ikeda T: Enhancing effect of thoracotomy and/or laparotomy on the development of the lung metastases in rats after intravenous inoculation of tumor cells. Jpn J Surg 1977, 7:263–268.PubMed 119. Tsukamoto T, Kinoshita H, Hirohashi K, Kubo S, Otani S: Human erythrocyte polyamine levels after partial hepatectomy. Hepatogastroenterology 1997, 44:744–750.PubMed 120. Aziz SM, Gillespie MN, Crooks PA, Tofiq SF, Tsuboi CP, Olson JW, Gosland MP: The potential of a novel polyamine transport inhibitor in cancer chemotherapy. J Pharmacol Exp Ther 1996, 278:185–192.PubMed 121.