IS629 prevalence in the A6 strains and the distribution Vactosertib supplier amongst Sp, SpLE, backbone and the pO157 plasmids
did not show any specific pattern, however it appears that IS629 transposes actively in the A6 CC. Table 3 IS629 element presence/absence in CC strains from the O157:H7 stepwise evolutionary model A6 A5 A4 A2 A1 A? A6 NR Phage Or backbone 1 2 3 4 5 6 7 8 9 10 11 12 Smoothened Agonist supplier 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 IS.1 Sp 4 ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS.2 Sp 4 ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS. 3 Sp 5 stx2 + – - – - – - – - – - – - – - – - – - – - – - – - + – IS. 4 SpLE 1 – + – - – - + – - – - – - – - – - – - – - – - – - – - IS. 5 SpLE 1 + + + + + – + – - – - – - – - – - – - – - – - – - + + IS. 6 SpLE 1 – + – - – - + – - – - – - – - – - – - – - – - – - – - IS. 7 SpLE 1 + + + + + – + + – - – - – - – - – - – - – - – - – + + IS. 8 Sp 8 + – + – + – + – - – - – - – - – - – - – - – - – - + – IS. 9 Sp 8 – + – - – - – - – - – - -
– - – - – - – - – - – - – + IS. 10 back + + – - + – + + – - – - – - – - – - – - – - – - – + + IS. 11 back + + – - + – - – - – - – - – - – - – - – - – - – - + + IS. 12 Sp 12 + – - – - – - – - – - + + + – - – - – - – - – - – + – IS. 13 back + + + + + + + – - – - – - – - – - – - – - – - – - + + IS. 14 Sp 13 + + + + + + – + – - – - – - – - – - – - – - – - – + + IS. 15 Sp 14 + + + + + + + + – - – - – - – - – - – - – - – - – + – IS.16 SpLE 2 ND ND ND https://www.selleckchem.com/products/Everolimus(RAD001).html ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS. 17 back + + – - – - – - Histidine ammonia-lyase – - – - – - – - – - – - – - – - – + + IS. 18 Sp 15 stx1 + + – - + – - – - – - – - – - – - – - – - – - – - + + IS. 19 back + – + + + – - + – - – - – - – - – - – - – - – - – + – IS. 20 Sp 17 + -
+ + + – + + – - – - – - – - – - – - – - – - – + – IS. 21 SpLE3 + + – + + + + + – - – - – - – - – - – - – - – - – + + IS.22 back ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS. 23 SpLE 5 + + – - + – + + – - – - – - – - – - – - – - – - – + + IS. 24 SpLE 1 – + – - – - – - – - – - – - – - – - – - – - – - – - + IS. 25 SpLE 1 – + – - – - – - – - – - – - – - – - – - – - – - – - + IS.26 933O ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS. 27 SpLE 2 – + – - – - – - – - – - – - – - – - – - – - – - – - + IS.28 933Y ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND ND IS. 29 Sp 1 – - + + – - – + – - – - – - – - – - – - – - – - – - – IS. 30 Sp 4 – - + – - – - – - – - – - – - – - – - – - – - – - – - IS. 31 Phage – - + + – - – - + + – + + + – - – - – - – - – - – - – IS. 32 back – - + + – - – + – - – - – - – - – - – - – - – - – - – IS. 33 Sp 13 – - + + – - – - – - – - – - – - – - – - – - – - – - – IS. 34 back – - + + – - – - – - – - – - – - – - – - – - – - – - – IS.