As we move

upward along the plate, the local Nusselt number starts to decrease after the optimal concentration level. For very high concentrations (as compared to optimal concentration level), the local Nusselt number initially increases near the lower end of the plate, and then its value becomes the smallest, and near the upper end of the plate, it becomes the highest, as shown in Figure 6a,b. This abnormal behavior at high concentrations may be due to the increased nanoparticle clustering with the increase in concentration of nanoparticles in the base fluid. Figure 7 depicts that with the increase in concentration of the nanoparticle in the base fluid, local skin friction coefficient increases. This is because of the increase in viscosity of the nanofluid FDA approval PARP inhibitor with the increase in concentration as given in Table 9. Dependence on particle diameter In this section, the effect of nanoparticle size on heat transfer and skin friction coefficient for Al2O3+ H2O nanofluid is discussed. Here, all the calculations have been done at click here 324 K (wall temperature). Figure 8a,b depicts that the

average Nusselt number as well as local Nusselt number both decrease with the increase in the size of nanoparticle. The reason for the deterioration in Nusselt number is the decreased thermal conductivity of the nanofluid with the increase in particle diameter. Similarly, the viscosity of the nanofluid decreases with the increase in particle diameter (given in Table 10); therefore, it decreases the skin friction coefficient. This

effect of particle size on the skin friction can be seen in the Figure 8c,d. These figures show that the average skin friction coefficient as well as the local skin friction coefficient both decrease with the increase in particle size. Figure 8 Nusselt numbers and skin friction coefficients for (a, b, c, d) different particle diameters. Table 10 Properties of Al 2 O 3  + H 2 O nanofluid for different particle diameters Properties Particle diameters d p (nm)   10 25 40 55 70 115 130 μ nf(10−3) 0.9198 0.8553 0.831 Dehydratase 0.8171 0.8077 0.7908 0.7871 k nf 0.8768 0.8007 0.7712 0.7542 0.7427 0.7222 0.7177 k eff 1.2167 1.1112 1.0703 1.0467 1.0307 1.0023 0.9961 α eff (10−6) 0.261 0.2384 0.2296 0.2245 0.2211 0.215 0.2137 Preff 3.1656 3.2229 3.2511 3.2687 3.2812 3.304 3.309 RaKeff 101.6243 119.6707 127.8621 132.9777 136.6173 143.4837 145.0528 T = 324, Φ = 0.04, and ε = 0.72. Comparison between different nanofluids In this section, six types of nanofluids have been studied. The comparative study of different nanofluids is shown in Figure 9 and Table 3. In the previous section, it has been found that the optimal concentration for the Al2O3 + water nanofluid at 324 K wall temperature is 0.04, and for maximum heat transfer rate, the particle diameter should be minimum. Therefore, we used this value of concentration and the particle diameter of 10 nm.